Product Name: 2,3,4-Trimethoxybenzaldehyde
Alias: Trimetazidine Impurity C
CASNo: 2103-57-3
Molecular Formula: C10H12O4
Molecular Weight: 196.20
Structural Formula: 
Appearance: White to pale yellow crystalline powder.
Storage: Store protected from light in a sealed container
Packaging: 25 kgs/drum
Capacity: 120 MT/year
Specification: Purity ≥99%
Applications of 2,3,4-Trimethoxybenzaldehyde
I. Pharmaceutical Field (Core Application)
As a key pharmaceutical intermediate, mainly used to synthesize the following drug classes:
Anti-angina drug — Trimetazidine
Core starting raw material / key intermediate for synthesizing trimetazidine.
Also serves as standard impurity C in trimetazidine quality control.
Antimigraine / cerebrovascular drug — Lomerizine Hydrochloride
Key building block as a calcium channel blocker for synthesizing lomerizine, used to treat migraine and cerebrovascular circulation disorders.
Alkaloids and antitumor drugs
Approximately 15% of global benzylisoquinoline alkaloid synthesis uses it as a starting material.
Used to construct benzene ring scaffolds for antitumor, antibacterial, and anti-inflammatory active molecules.
Other cardiovascular drugs
Used in synthesizing anti-arrhythmia and antihypertensive drugs such as carocainide hydrochloride.
II. Fragrance and Personal Care
Synthesis of novel fragrances: Through reduction, condensation and other reactions, prepare trimethoxybenzyl alcohol and various aromatic acetals as fixatives and modifiers for premium perfumes, cosmetics and soap fragrances.
Vanillin derivative alternative: More stable aroma, used for flavor enhancement and taste correction in food and tobacco.
III. Fine Chemicals and Materials
Organic synthesis building block: Construct multi-substituted benzene rings for intermediates in liquid crystals, dyes, and photosensitive materials.
Metal complex ligands: Chelate with metal ions for catalysts, chemical sensors, and heavy metal adsorption materials.
Electronic chemicals: High-purity grade used as additive in semiconductor photoresists and packaging materials.
IV. Research and Analysis
Reference standard: As trimetazidine impurity reference for drug development, quality testing and registration.
Reaction model: Study nucleophilic addition, condensation, methylation and other organic reaction mechanisms.
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